I have a Media player,when it boots it comes up with No Disk on the players screen, There is a hard drive a 250gb,it works fine Iv tried in a caddie. I have used the USB connection to the PC, but there is nothing there, Iv tried Device manager etc, but nothing.
Either your HDD is dead or your HDD enclosure is dead. I would suggest getting a replacement HDD enclosure and trying your HDD in it.