You sure can and it works well! AnyDVD works as a driver, and as long as you are using it in the "auto load when windows starts" then it will be up and running right after the DVD and before RatDVD. I just finished testing it. Took a long time, but then I am using it on a 2GB CPU, and that is below the recomended speed./ Sure is amazing at how much compressions is acheved, with as good a quality end result. Kudo's to the folks that worked so hard on it!