IMHO, none of the tools can handle AVIs with that size. Still, how did you create the file? I mean, did you try to rip some movie or...?
i downloaded a movie from the web and i wanted to split the movie into 2 parts. i set a start and an end in the middle so the movie was devided and i deleted the last frame after the end in the middle and then i just saved the file
And forgot to change the Video and Audio settings, I assume. We have a guide for AVI splitting on our guides section, read it from here: http://www.afterdawn.com/articles/